Product Code: CAS 154992-24-2
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RU58841 Quick Details:

RU-58841 RU58841 Quack Detail
Application    Specific androgen receptor antagonist
CAS    154992-24-2
Molar Mass    369.34 g/mol
Chemical Formula    C17H18F3N3O3
Synonyms    PSK-3841, HMR-3841
Storage    Minimize open air exposure, store in a cool dry place
Reports    FT-IR/HPLC


Specification
 

Product Name:RU58841
Synonyms:4-(4,4-Dimethyl-2,5-dioxo-3-(4-hydroxybutyl)1-imidazolidinyl)-2-(trifluoromethyl)benzonitrile; RU58841; 4-[3-(4-Hydroxybutyl)-4,4-dimethyl-2,5-dioxo-1-imidazolidinyl]-2-(trifluoromethyl)benzonitrile
CAS RN.:154992-24-2
Molecular Weight:369.3383
Molecular Formula:C17H18F3N3O3
Density:1.39g/cm3
Boiling Point(C):493.6C at 760 mmHg
Flash Point(C):252.3C
refractive_index:1.559





Active Pharmaceutical Ingredients Steroid Ru-58841 CAS 154992-24-2 for Hair Loss



Usage:

RU 58841 is a specific androgen receptor antagonist or anti-androgen used as a topical treatment for acne, androgenetic alopecia and hirsutism. RU 58841 displays high affinity for the hamster prostate and flank organ (F.O.) androgen receptors. In vivo, when topically applied, it exerts a potent dose-dependent regression of F.O. area at a dose as low as 1 microgram/animal while being devoid of antiandrogenic activity on deep accessory sex organs and of any effect on test level up to 100 micrograms/animal. RU 58841 has a dramatic effect on hair regrowth


Description:

RU-58841 is a new non-steroidal specific topical antiandrogen: a candidate of choice for the treatment of acne, androgenetic alopecia and hirsutism. The potent localized inhibition of sebaceous glands by RU 58841 demonstrates the excellent potential of this compound as a topical drug for the treatment of acne and other androgen-mediated disorders. Synonym: RU-58841; RU58841; RU 58841. 
RU58841 is the drug for the treatment of hair loss dwindled, perhaps due more to commercial potential and chemical stability reasons than efficacy as the later studies of RU58841 have focused on different chemical forms of the drug and combining it with various nanoparticles to enhance delivery.
the drug for the treatment of hair loss dwindled, perhaps due more to commercial potential and chemical stability reasons than efficacy as the later studies of RU58841 have focused on different chemical forms of the drug and combining it with various nanoparticles to enhance delivery. Recent years have seen the odd study pop up in relation to RU58841 and the treatment of acne and prostate cancer, which are conditions also driven however, the most recent study published in relation to RU58841 was back in 2008.

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